The Concentration of Digoxin Activity after Intravenous in Three Compartments Mathematical Model
Lakshmi Narayan. K1, Siva Rama Krishna Reddy. V2
1Lakshmi Narayan. K, Department of Mathematics, Vidya Jyothi Institute of Technology, Hyderabad (Telangana), India.
2Siva Rama Krishna Reddy. V, Department of Mathematics, Gokaraju Rangaraju Institute of Engineering and Technology, Hyderabad (Telangana), India.
Manuscript received on 19 October 2019 | Revised Manuscript received on 25 October 2019 | Manuscript Published on 02 November 2019 | PP: 3653-3657 | Volume-8 Issue-2S11 September 2019 | Retrieval Number: B14600982S1119/2019©BEIESP | DOI: 10.35940/ijrte.B1460.0982S1119
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Abstract: Present paper is designed to compare the distribution of digoxin in three compartment model administered through an intravenous (i.v). These models under consideration is denoted by a system of non-linear ordinary differential equations. The Eigenvalue and the Laplace transform methods were used to solve the system of equations. Digoxin was administered to five subjects through Intravenous then, the serum digoxin concentrations were measured respectively over a period of 72 hours. The transfer coefficients were obtained from observed digoxin concentrations using method of residuals and the variation of digoxin concentration – time curves plotted using MATLAB.
Keywords: Digoxin, Blood Plasma, Intestinal Fluid, Cells, Laplace Transform, Eigenvalue.
Scope of the Article: Cryptography and Applied Mathematics