Cytitoxic Activity from the Tuber of Cassava (ManihotesculentaCrantz) Against Servical Hela Cancer Lines
Diana Widiastuti1, Supriatno Salam2, Desi Haneti3, Ronny Lesmanaand4, Unang Supratman5
1Diana Widiastuti, Department of Chemistry, Faculty of Mathematics and Natural Science, Pakuan University, Indonesia.
2Supriantno Salam, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Indonesia.
3Desi Hanaeti, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Indonesia.
4Ronny Lesmana, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Indonesia.
5Unang Supriatman, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Indonesia.
Manuscript received on 03 August 2019 | Revised Manuscript received on 26 August 2019 | Manuscript Published on 05 September 2019 | PP: 243-244 | Volume-8 Issue-2S7 July 2019 | Retrieval Number: B10620782S719/2019©BEIESP | DOI: 10.35940/ijrte.B1062.0782S719
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: This research evaluated the cytotoxic effect of the extract of cassava (M. Esculentacrantzs) againtsservical Hela cancer line. The tuber of Cassava is first extracted with ethanol at room temperature. The ethanol extract was dissolved in water and the partitioned successively with n-hexane and n-butanol. All of the extract were evaluated their cytototoxic activity againstservicalHela cancer line in vitro using MTT methods. The results indicate that the n-butanol showed strongerst cytotoxic activity with IC50 value of 1.07 ug/mL.
Keywords: Cytotoxic Activity, Cervical Hela Cancer Cells, Cassava Sao Pedro Petro, Manihotesculenta Crantz.
Scope of the Article: Bio-Science and Bio-Technology